Otto-von-Guericke-Universität Magdeburg

University Department of Neurology
 
 
 
 
 
 
 
 
 
 
 
 
01team_MRT
 

Magnetic Resonance Imaging

Head

Dr. rer. nat. Claus Tempelmann (Physicist)

Staff

Dr. rer. nat. Martin Kanowski (Physicist)
Dr. rer. nat. Jörn Kaufmann (Physicist)
Kerstin Möhring (MTRA)
Denise Scheermann (MTRA)
Ilona Wiedenhöft (MTRA)

Collaborations

» University Hospital Magdeburg
» Leibniz Institute for Neurobiology Magdeburg
» Otto-von-Guericke-University Magdeburg
» Max Planck Institute for Human Development Berlin
» University Hospital Hamburg-Eppendorf
» University Hospital Jena
» University Hospital Hannover
» University Hospital Lübeck
» University of Zurich, Switzerland
» University of Barcelona, Spain
 

Overview

The Department of Neurology currently operates a 3-Tesla magnetic resonance imaging scanner (Trio Siemens) for research purposes. A 1.5-Tesla tomograph (General Electric) was used until December 2011. Moreover, the clinic has access to the first European 7-Tesla scanner for applications in humans, installed at the Leibniz Institute for Neurobiology. In addition, the clinic gets scan time at the 3-Tesla scanner (Verio Siemens) at the German Center for Neurodegenerative Diseases (DZNE) in Magdeburg. These scanners are all shared by several research groups both within and outside the clinic and are used for both basic cognitive and clinical research projects in neurology. Working in conjunction with these partners, the primary concern of the magnetic resonance imaging group is the development and improvement of acquisition and analysis tools for various MR methods. Along with the classical structural imaging sequences, the most important MR methods adopted for clinical research in neurology are functional BOLD imaging, magnetization transfer imaging, susceptibility weighted imaging, angiography, and diffusion weighted imaging including tensor diffusion imaging and proton spectroscopy. The results of many of the MR projects conducted by the Dept. of Neurology can be seen in other sections of this booklet. Here, In this part we will focus on technical and methodological developments.

» Diffusion Weighted Imaging
» Analysis of structural MR data
» Proton spectroscopy
» Functional Brain Imaging (fMRI)

Clinical Studies

For the staff of the Magnetic Resonance Imaging lab the main focus lies on methodological developments, basic research, and providing advisory and support services for the research partners. However, we have also been partners in numerous clinical studies in the fields of multiple sclerosis, amyotrophic lateral sclerosis, epilepsy, stroke, memory impairment, attention deficit disorders, movement disorders, depression and schizophrenia.

Selected Publications

Buentjen L, Kopitzki K, Schmitt FC, Voges J, Tempelmann C, Kaufmann J, Kanowski M. Direct Targeting of the Thalamic Anteroventral Nucleus for Deep Brain Stimulation by T1‑Weighted Magnetic Resonance Imaging at 3 T. Stereotact Funct Neurosurg. 2014;92:25-30.

Schuster C, Kasper E, Machts J, Bittner D, Kaufmann J, Benecke R, Teipel S, Vielhaber S, Prudlo. Focal thinning of the motor cortex mirrors clinical features of amyotrophic lateral sclerosis and their phenotypes: a neuroimaging study.  J. J. Neurol. 2013 Nov; 260(11):2856-64.

Hoefer M, Tyll S, Kanowski M, Brosch M, Schoenfeld MA, Heinze HJ, Noesselt T. Tactile stimulation and hemispheric asymmetries modulate auditory perception and neural responses in primary auditory cortex. Neuroimage. 2013 Oct 1;79:371-82.

Ash T, Suckling J, Walter M, Ooi C, Tempelmann C, Carpener A, Williams G. Detection of physiological noise in resting state fMRI using machine learning. Hum Brain Mapp. 2013 Apr;34(4):985-98.

Zierhut KC, Graßmann R, Kaufmann J, Steiner J, Bogerts B, Schiltz K. Hippocampal CA1 deformity is related to symptom severity and antipsychotic dosage in schizophrenia. Brain. 2013 Mar;136(Pt 3):804-14.

Boelmans K, Kaufmann J, Schmelzer S, Vielhaber S, Kornhuber M, Münchau A, Zierz S, Gaul C. Hirayama disease is a pure spinal motor neuron disorder - a combined DTI and transcranial magnetic stimulation study. J Neurol. 2013 Feb;260(2):540-8.

Bittner DM, Heinze HJ, Kaufmann J. Association of 1H-MR spectroscopy and cerebrospinal fluid biomarkers in alzheimer's disease: diverging behavior at three different brain regions. J Alzheimers Dis. 2013 Jan 1;36(1):155-63.

» more...
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Last Modification: 27.06.2018 - Contact Person: Ögelin Düzel
 
 
 
 

CANLAB
  » CANLAB - Clinical Affective
Neuroimaging Laboratory


Demenz und kognitive Störung
  » Dementia/Cognitive
Disorders


Memory and Consciousness
  » Memory and Consciousness


Magnetresonanztomographie
  » Magnetic Resonance Imaging


MEG
  » MEG


Neuropsycholgie
  » Neuropsychology


Restaurative Neurologie
  » Restaurative Neurology


Mischpathologien des zerebralen Alterns
  » Mixed cerebral pathologies
and cognitive aging


Brain Machine Interface
  » Brain Machine Interface